This is a Google Bard AI summary of the Tim Ferriss Podcast #610- visit www.TinyTim.blog for more AI summaries, or www.Tim.blog for the official Tim Ferriss Podcasts.

**The Life Extension Episode**
* This episode of the Life Extension Podcast features Dr. Matt Kaeberlein, a professor of
pathology and bioengineering at the University of Washington. Kaeberlein is the director of
the Dog Aging Project, a research initiative that is using a variety of methods to study
aging in dogs.
* In the episode, Kaeberlein discusses the challenges of studying aging, the potential
benefits of extending lifespan, and some of the most promising research being done in this
area.
**The Dog Aging Project**
* The Dog Aging Project is a research initiative that is using a variety of methods to study
aging in dogs. The project is funded by the National Institutes of Health and is led by Dr.
Matt Kaeberlein.
* The Dog Aging Project is studying a large group of dogs of different breeds and ages.
The dogs are being monitored for a variety of factors, including their health, behavior, and
lifespan.
* The goal of the Dog Aging Project is to identify the biological mechanisms that drive
aging and to develop interventions that can extend lifespan.
**Rapamycin**
* Rapamycin is a drug that is used to prevent organ rejection in transplant patients.
Rapamycin has also been shown to extend lifespan in mice.
* The Dog Aging Project is studying the effects of rapamycin on aging in dogs. The
preliminary results suggest that rapamycin can extend lifespan in dogs.
**Metformin**
* Metformin is a drug that is used to treat type 2 diabetes. Metformin has also been shown
to extend lifespan in mice.
* The Dog Aging Project is studying the effects of metformin on aging in dogs. The
preliminary results suggest that metformin can extend lifespan in dogs.**Spermidine**
* Spermidine is a compound that is found in many foods, including dairy products, eggs,
and nuts. Spermidine has been shown to extend lifespan in mice.
* The Dog Aging Project is studying the effects of spermidine on aging in dogs. The
preliminary results suggest that spermidine can extend lifespan in dogs.
**NAD Precursors**
* NAD is a coenzyme that is essential for many cellular processes. NAD levels decline with
age.
* NAD precursors are compounds that can be converted into NAD in the body. NAD
precursors have been shown to extend lifespan in mice.
* The Dog Aging Project is studying the effects of NAD precursors on aging in dogs. The
preliminary results suggest that NAD precursors can extend lifespan in dogs.
**Urolithin A**
* Urolithin A is a compound that is produced by the gut microbiome when we eat certain
foods, such as berries and nuts. Urolithin A has been shown to extend lifespan in mice.
* The Dog Aging Project is studying the effects of urolithin A on aging in dogs. The
preliminary results suggest that urolithin A can extend lifespan in dogs.
**Acarbose**
* Acarbose is a drug that is used to treat type 2 diabetes. Acarbose has also been shown
to extend lifespan in mice.
* The Dog Aging Project is studying the effects of acarbose on aging in dogs. The
preliminary results suggest that acarbose can extend lifespan in dogs.
**Conclusion**
* The research being done by the Dog Aging Project and other research initiatives is
providing hope that we may one day be able to extend lifespan in humans. However, more
research is needed before we can say for sure if these interventions will be safe and
effective in humans.
610) https://tim.blog/2022/07/27/matt-kaeberlein-life-extension/